r/migrainescience is a subreddit with 9k members. The most common kinds of discussions are pain & anger and advice requests, and the community frequently discusses migraine, study, treatment, headache, and prevention.
The science behind migraine disease, or any type of headache, and migraine news. (Extension of Cerebral Torque's blog)
Popular Themes in r/migrainescience
#1
Pain & Anger
: "This study found that migraine affects cognitive abilities like attention, memory, and processing speed both during attacks and between them, with these cognitive problems being as disabling as the pain itself and occurring even when headaches aren't present."
6 posts
#2
Advice Requests
: "This article proposes a new migraine subtype called "migraine with associated myofascial pain" (MAMP) that describes migraine patients who experience persistent neck, shoulder, and upper back pain. The authors believe "it may serve as a clinical bridge between migraine, corpalgia, and fibromyalgia.""
6 posts
#3
News
: "Quick comments on the increased popularity of the ketogenic diet for migraine"
2 posts
#4
Solution Requests
: "This study found that STS101, a new nasal powder form of a migraine medication (Atzumi), was easy to use for over 90% of people and worked faster than their previous treatments, with most people becoming pain-free within 4 to 24 hours after using it."
1 post
#5
Money Talk
: "The study found that patients w/ migraine taking Emgality (galcanezumab), Ajovy (fremanezumab), or Aimovig (erenumab) experienced increased total healthcare costs due to the high price of these meds that outweighed any savings from reduced emergency room visits and other medical resources use."
1 post
#6
Self-Promotion
: "I have decided to make the kindle edition of Unraveling Migraine completely FREE starting 3:00 AM EST on Monday, February 10, 2025 for 48 hours. Evidence-based migraine education is incredibly necessary now more than ever."
1 post
Popular Topics in r/migrainescience
#1
Migraine
: "This study found that things people often blame for starting their Migraine attacks (like bright lights [photophobia] or loud sounds [phonophobia]) might actually be the first signs that a Migraine attack has already begun in the brain, not the actual cause of the Migraine attacks."
399 posts
#2
Study
: "This Study found that things people often blame for starting their migraine attacks (like bright lights [photophobia] or loud sounds [phonophobia]) might actually be the first signs that a migraine attack has already begun in the brain, not the actual cause of the migraine attacks."
216 posts
#3
Treatment
: "This study found that migraine creates a challenging cycle where the condition itself is disabling, but the lack of understanding and judgment from others (including healthcare providers) makes it even harder for people to get the support and Treatment they need."
119 posts
#4
Headache
: "This study found that migraine patients had distinct oral microbiome alterations compared to healthy controls, with specific bacterial genera correlating with Headache frequency. These oral microbial signatures could accurately classify migraine status using machine learning."
31 posts
#5
Prevention
: "The International Headache Society just released new standards for migraine Prevention!"
30 posts
#6
Brain
: "This study found that chronic migraine causes overactive Brain cells in the visual cortex (the Brain area that processes vision), and this overactivity is specifically linked to light sensitivity rather than headache pain itself."
28 posts
#7
Patients
: "This study found that while Patients with high-frequency/chronic migraine had lower vitamin D levels than healthy controls, this deficiency was not correlated with headache frequency or CGRP levels. This means it may be a consequence of migraine on lifestyle rather than a cause of migraine"
26 posts
#8
Cgrp
: "Anti-Cgrp Monoclonal Antibody Super-Responders and Absolute Responders and When to Expect Results"
24 posts
#9
Chronic
: "This study found that nearly half of adults with Chronic headaches (15 or more days per month) also experience depression or anxiety, at rates 2 to 7 times higher than people with occasional or no headaches. This reinforces why mental health screening is important for these patients."
15 posts
#10
Pain
: "This article proposes a new migraine subtype called "migraine with associated myofascial Pain" (MAMP) that describes migraine patients who experience persistent neck, shoulder, and upper back Pain. The authors believe "it may serve as a clinical bridge between migraine, corpalgia, and fibromyalgia.""
13 posts
Flair Used in r/migrainescience
#1
Science
: "This study found that things people often blame for starting their migraine attacks (like bright lights [photophobia] or loud sounds [phonophobia]) might actually be the first signs that a migraine attack has already begun in the brain, not the actual cause of the migraine attacks."
132 posts
#2
Misc
: "Almost finished with the second edition of Unraveling Migraine. It's over 300 pages, but still concise and informative. Everything is updated and current. Included is a significant section specific to women's health. Thank you for your patience as I know this subreddit has been lacking recently."
36 posts
#3
Study Analysis
: "New Emergency Department Migraine Treatment Guidelines (Save this!)"
5 posts
#4
From Cerebral Torque
: "This study found that migraine has a causal relationship with increased risk of cochlear diseases, including a 52% higher risk of tinnitus and 63% higher risk of vertigo"
4 posts
#5
Instagram
: "For decades, migraine gold-standard treatments were studied without analyzing response by sex. This shows up everywhere....triptans behave differently in women, CGRP antibodies need months of washout before pregnancy, hormones change drug responses, etc. More sex-aware prescribing is necessary."
3 posts
#6
MigraineScience YouTube
: "I did a live Q&A on migraine and hormones recently, but it's behind a paywall so I uploaded it for you guys. Hope it helps!"
3 posts
#7
Science/Study analysis on blog
: "I posted concerns about left vs right-sided migraine research on Instagram 2 months ago. A prominent person connected to the lead author warned me against "personally attacking colleagues in a small field." I was then impacted professionally shortly after. Here's the full critique with sources."
2 posts
#8
News
: "The TEMPLE trial found that atogepant (Qulipta, a gepant) significantly outperformed topiramate (Topamax) for migraine prevention, with fewer patients dropping out due to side effects (12.1% vs 29.6%) and more patients achieving at least a 50% reduction in monthly migraine days (64.1% vs 39.3%)."
2 posts
Member Growth in r/migrainescience
Yearly
+3k members(40.3%)
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Last updated: June 14, 2026