Antidepressants reviews from Reddit
Summary
We analyzed 153 Reddit reviews across 29 subreddits and 43 posts to rank the best Antidepressants brands recommended by redditors, including communities like r/antidepressants, r/migraine, r/Fibromyalgia, r/Wellbutrin_Bupropion, r/BeyondTheBumpUK. Top-rated brands include Sertraline (4.3/5), Duloxetine (3.8/5), Wellbutrin (3.9/5).
Stats
Reviews153
Subreddits29
Posts43
Brands54
Products5
153 reviews from
and
By Brand
/By Product
#1
Sertraline
4.3
(19)
"I have anxiety and depression and take Zoloft. And saw no issues with both the Real Scary Shit (Ambien) and the chiller shit (Trazadone)."
"It was life changing for me."
"Started Sertraline recently (around 9 months pp) as my postnatal depression shifted into extreme PMS."
"It has been a life saver for me."
"It honestly changed my life and that of my little one."
"The sertraline works much better for me and is safe to take while breastfeeding."
"I started Zoloft while pregnant last year. No joke, it radically changed my life."
"I’ve been on Zoloft 100 mg for 5 years and am its biggest advocate!"
"Going on Zoloft was the best decision I made this pregnancy."
"I met with 3 psych providers before taking the plunge with one who focused on perinatal care."
#2
Duloxetine
3.8
(11)
"Cymbalta"
"Mine saved my life.. cymbalta and then LDN finally got me to a manageable place."
"I’m on Duloxetine which I understand can help with both anxiety and depression."
"I'd say give it a try."
"Cymbalta/duloxetine."
"I started duloxetine, I’ve been titrating slowly and currently at 90 mg for both fibromyalgia and to complement the lamotrigine for bipolar depression."
"Ive been on duloxetine for two years."
"I am currently trying duloxetine so general pain as it's been shown to help."
"I started with duloxetine and it sucked."
"I didn't have depression before starting cymbalta."
#3
Wellbutrin
3.9
(10)
"I love Wellbutrin. It’s been a life changed for me."
"However, Welbutrin (generic is bupropion) has been great."
"I made the switch from venlafaxine to wellbutrin and mirtazapine and it has helped a lot."
"Ppl say that Bupropion (Wellbutrin) has no effect on sex life, but it's better for depression."
"Wellbutrin worked better than Effexor and sertraline for me."
"I switched to Wellbutrin. It does help more with energy and not feeling like a zombie."
"For me, Wellbutrin didn’t give me the lifeless feeling that other meds gave me."
"I'm on Wellbutrin and will occasionally drink cocktails."
"I take 300mg Wellbutrin, and am about to add on Moclobemide, because it’s not enough."
"I couldn't handle wellbutrin."
#4
Nortriptyline
4.0
(8)
"Nortriptyline has worked well as a preventative for my migraines."
"Nortriptyline was working very well for me as an add-on to Wellbutrin."
"I’m on nortriptalyne now and it’s been the only medication that has helped."
"I used nortriptyline with minimal side effects after the first 6 weeks or so. It did help me sleep, which was a bonus given that I deal with insomnia regularly."
"Nortriptyline has helped decrease the severity of my migraines by a ton, and has also made a huge improvement on my anxiety and depressive episodes."
"Nortriptyline in a low dose has made a significant difference."
"I was on nortiptyline for 2 years and it helped a lot with the pain."
"I’m trying to switch from mirt to nortriptyline but idk if that’s the right choice."
#5
Amitriptyline
3.8
(8)
"I take Amitriptyline, which is TCA, and it has been wonderful in my journey with fibro."
"I did feel a decrease in intensity of the migraines."
"I went from daily migraines to once every couple months."
"No side effects from the anti depre"
"I’ve taken up to 125 mg Amitryptiline with no issues."
"I'm on amitriptyline for sleep + migraines + arthritis pain."
"I take Amitriptyline 150 mg before bed to help me fall asleep."
"I’ve just come off 3 weeks of 10mg amitriptyline with nothing to show for it."
#6
Bupropion
4.3
(7)
"I would say for dépression bupriprion is the best"
"I take wellbutrin for my emotional regulation and it helps a lot."
"Wellbutrin has given me energy."
"Wellbutrin helps me after a couple of weeks."
"Wellbutrin is easy to try."
"I'm hoping the supposed motivational and energy boost will help."
"It gives me energy and productivity to get through the day."
#7
Escitalopram
4.1
(7)
"Lexapro changed my life."
"I am taking lexapro more so for anxiety but everything has gone smoothly so far."
"I started Lexapro 2yrs ago and it’s been a GAME CHANGER!"
"Lexapro has really helped mine, and it also worked really well on my aphasia!"
"Wow Lexapro was the go to for least amount of AEs out of those SSRIs."
"I am now on fluoxetine and low BP, maybe your first choice, but if not try effexor."
"Many people have good experience with lexapro!"
#8
Mirtazapine
4.0
(7)
"For me personally, mirtazapine actually works to reduce anxiety, and insomnia."
"Mirtazapine helped me with chronic fatigue"
"Yes try Mirtazapine."
"It helped to make my sleep better."
"I wouldn’t be writing this on mirtazapine. My mind clearer and weed feels better when u not in zombie mode."
"Mirt is better for sleep/ energy for me."
"For people who only have issues with insomnia and not depression or anxiety, the common meds are mirtazapine 7.5 mg."
#9
Venlafaxine
4.2
(6)
"Hi I’ve been on anxiety meds for years now. I’m on Effexor even."
"Effexor + lithium here for years. It works, it works really-really well."
"It definitely reduced the frequency and intensity of the migraines."
"You should try Effexor-Venlafaxine."
"I take 75mg Effexor XR daily and it does help with the pain."
"I’m having some success with clomipramine now but rougher side effects."
#10
Fluoxetine
4.8
(4)
"I'm now on fluoxetine and feeling great on it."
"It helps with pain and the entire severity of my migraine."
"I am currently taking a low dose of Prozac and am feeling great."
"I switched to fluoxetine for depression which seemed to work."
#11
Citalopram
4.3
(4)
"I got given 10mg of citalopram and I."
"I switched to citalopram which is now, I think, working for me."
"Not many side effects, to be honest."
"They work pretty good."
#12
Prozac
3.8
(4)
"First id try probs fluoxetine"
"Prozac has been good to me."
"Prozac has helped me, mainly with SA and depression."
"Not a doctor, but I suggest asking about anti-depressants that are not SSRIs like Prozac."
#13
Trazodone
4.7
(3)
"It’s a very old antidepressant from the 60’s, so it has a long history of safe use."
"I take 100mg of trazadone and it helps SO MUCH."
"Trazodone is common for insomnia- it's an antidepressant."
#14
Cymbalta
2.8
(4)
"Cymbalta is proven as a migraine treatment, it was recommended by my headache clinic."
"Cymbalta, Gabapentin, LDN."
"Well if you take Cymbalta you’re totally stuck with it."
"I would avoid it like the plague. It was awful, didn't help for migraines and no doctor would take me off / change it out."
#15
Lexapro
3.3
(3)
"I was on antidepressants when diagnosed with anxiety and depression as a teenager."
"It doesn't numb me like lexapro and it has helped tremendously with my binge eating issues."
"I don't love the lexapro side effects, and going on/off SSRIs is rough, but it does really help my anxiety."
#16
Lamotrigine
5.0
(2)
"Maybe try a combo of lamotrigine and gabapentin! That really helped me until I didn’t need them anymore."
"The antipsychotic Lamotrigine worked incredibly well for lifting my mood."
#17
Phenelzine
4.5
(2)
"Nardil (MAOI) is still the best thing I’ve tried."
"The symptoms of the 3 of them were greatly reduced."
#18
Zoloft
4.5
(2)
"It helped my anxiety A LOT."
"Zoloft has been helping me a lot it's the only antidepressant so far that hasn't made me eat a lot"
#19
Fluvoxamine
4.0
(2)
"Fluvoxamine (brand names: Luvox, Fevarin) is helped me a lot."
"I was switched to Luvox and it helped."
#20
Doxepin
4.0
(2)
"Afaik doxepin is most sedating TCA, so probably will work good for sleep."
"I take low dose doxepin and agomelatin for sleep which help a decent amount."
#21
Low Dose Naltrexone
4.0
(2)
"Maybe have a look at Low Dose Naltrexone. My rheumatologist has prescribed this for me from a compound pharmacy."
"Look into low dose naltrexone."
#22
Magnesium
4.0
(2)
"I've found that my migraines are less intense now."
"Magnesium supplements help."
#23
Antidepressants
3.5
(2)
"My wife has taken antidepressants for her postpartum after each of our kids were born."
"I also am in need of antidepressants because being chronically ill from SIBO caused depression for me."
#24
SSRIs
3.5
(2)
"The answer is that for OCD, the main antidepressants used are SSRIs, or sometimes the tricyclic clomipramine."
"Some people have luck with SSRIs, give it a try."
#25
Trintillex
5.0
(1)
"Trintillex by far was best for me"
#26
Psilocybin
5.0
(1)
"Microdosing psylocibin! Seriously worth a try."
#27
Myo-Inositol
5.0
(1)
"Supplement called Myo-Inositol! Life changing!"
#28
Nardil
5.0
(1)
"I suggest Nardil. It's the only antidepressant that has worked for me."
#29
Vilazodone
5.0
(1)
"Yes with viibryd. helps a lot."
#30
Lithium
5.0
(1)
"I took lithium and seroquel for three years and it was incredibly effective!"
#31
SNRIs
5.0
(1)
"I take an SNRI that has been life changing."
#32
Pregabalin
5.0
(1)
"I personally take lyrica which is technically an anti-convulsant and it’s been so much better than anything I took before."
#33
Caplyta
5.0
(1)
"Caplyta and Lamictal"
#34
Effexor
5.0
(1)
"Effexor/Venlafaxine + Carbamazepine have been working great"
#35
Viibryd
4.0
(1)
"I take viibryd, it’s really the only thing that’s works for me."
#36
Celexa
4.0
(1)
"I've had success with celexa and effexor."
#37
Auvelity
4.0
(1)
"Auvelity."
#38
Silexan
4.0
(1)
"Silexan."
#39
Cannabis
4.0
(1)
"Cannabis."
#40
Gravol
4.0
(1)
"Gravol helps me, helps with anxiety so much."
#41
Lamictal
4.0
(1)
"Lamictal! Technically anti seizure med and I like it a lot."
#42
Buspirone
4.0
(1)
"I would definitely give buspar a try, it's waiting to chill."
#43
Trintellix
4.0
(1)
"Try trintellix."
#44
SNRI
4.0
(1)
"Why not stack an SNRI with a betablocker?"
#45
Tranylcypromine
4.0
(1)
"Fluoxetine. Parnate."
#46
Protriptyline
4.0
(1)
"Probably protriptyline."
#47
Clomipramine
4.0
(1)
"Clomipramine and bupropion."
#48
TCA Antidepressants
4.0
(1)
"TCA antidepressants are preferred while those with constipation can be given SSRIs."
#49
Paroxetine
4.0
(1)
"Paroxetine didn’t do anything for the first week or so, but I stuck with it and the difference is night and day."
#50
Desvenlafaxine
4.0
(1)
"Pristiq or cymbalta!"
#51
St John's Wort
4.0
(1)
"Worked surprisingly well."
#52
5-HTP
3.0
(1)
"5-htp, over the counter."
#53
Gabapentin
3.0
(1)
"There is gabapentin and Lyrica that are known to work well for people for me I just couldn’t handle the side effects."
#54
MigraKet
3.0
(1)
"I found that MigraKet worked pretty well for me."
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