Biologic reviews from Reddit

Summary

We analyzed 274 Reddit reviews across 16 subreddits and 55 posts to rank the best Biologic brands recommended by redditors, including communities like r/UlcerativeColitis, r/CrohnsDisease, r/PsoriaticArthritis, r/Psoriasis, r/ankylosingspondylitis. Top-rated brands include Entyvio (4.1/5), Humira (3.8/5), Remicade (4.0/5).

Stats
Reviews274
Subreddits16
Posts55
Brands49
Products21
274 reviews from
and
By Brand
/
By Product
#1

Entyvio

4.1
(32)
"My GI reviewed my case and said he would have just put me straight on Entyvio, which I’m on now. Been on it for 1.5 years doing well!"
·
"Been on it for 1.5 years doing well!"
·
"I've been on Entyvio for almost 4 years now and I've noticed noooo change in my immunity."
·
"Don’t be afraid, it’s way better than having a bleeding butthole lol"
·
"Entyvio has allowed me so much freedom."
·
"Entyvio has the best safely profile. If I were starting biologics I'd pick that one."
·
"Entyvio is the only gut selective biologic, all the others do have some degree of systemic effects."
·
"It doesn’t really immune compromise you because it’s gut targeted."
·
"The 'safest' one with least side effects and most specific to our condition is Entyvio."
·
"I am on month 3 I believe of entyvio and it seems to be helping for my terminal ileum crohns."
·
#2

Humira

3.8
(34)
"I’m on a different biologic (Humira) but I love it. Very minimal side effects and it keeps me in remission."
·
"I’ve been on Humira for about 6 years. It was like a miracle."
·
"I have nothing bad to say about humira, I’m clear and it’s preventing arthritis. The injections are not painful at all. It’s a life changing medication for me."
·
"I used the one I got from humira! I got it for free, I just had to tell them I needed one"
·
"Humira and Taltz were best for it."
·
"Better on the tummy, couldn’t make it thru the dosing window."
·
"I’ve done Enbrel and Humira in the stomach. It’s super easy and pain free."
·
"I tried Cimzia for a few years and really liked it until I developed antibodies and it wasn’t working for me anymore, switched to humira, which worked for a number of years."
·
"I personally am on Humira, and it's helped me greatly."
·
"I started Remicade in 2019 and would make that decision again."
·
#3

Remicade

4.0
(23)
"I started on Remicade and it worked overnight like magic."
·
"10 years and counting on remicade and in a remission thanks to it."
·
"I was put on Remicade in Hospital right away when diagnosed 3yrs ago. It put me into remission and has kept me there for the past 3yrs."
·
"Heavily promoted biologics. He said I couldn’t continue in this destructive cycle."
·
"Remicade literally saved my life and has kept me in remission for years."
·
"I feel like it saved my life and allows me to be able to do and eat more than I thought I was going to be able to."
·
"It was a miracle drug for me at that time."
·
"Remicade is supposed to have high success rate but Rinvoq beat it."
·
"Was put on Remicade (Infliximab) (Diagnosed Dec. 2018) Remission for roughly 1 1/2 years."
·
"Started on infliximab and still on it. It has been effective for 6 months so far."
·
#4

Biologics

4.3
(20)
"Cannot advocate hard enough for starting on a biologic."
·
"Don't do steroids, go on the biologic directly. It's clearly the superior option."
·
"Definitely go on biologics 1st. It's increasing common to put new patients on biological meds to give patients a good quality of life fast."
·
"It did give me my life back and my quality of life has been good."
·
"Biologics completely changed my life for the better."
·
"I've been on a biologic for more than a year. It hasn't caused me any problem and it works so well."
·
"Definitely do it… I was hospitalized once and started biologics 2 years ago and have not been hospitalized since."
·
"It’s life changing when you find the one that works!"
·
"Been on biologics for 13 years. They work. Few side effects."
·
"My skin fully cleared within a month on biologics, within 2-3 all the nails as well! 0 side effects."
·
#5

Stelara

4.1
(20)
"Most relief I've had has been stelara every 4 weeks ! Finally able to start to taper off predisone after 1.5years !"
·
"Way way way better than prednisone, since I started the biologic stelara (2020) I've pooped like once or 2 times per day."
·
"I started a biologic in November stelara and I’m in remission since January."
·
"Stelara works very well for both my Crohn’s and psoriasis."
·
"I’d choose stelara. You can self inject + leave at room temp for up to 30 days."
·
"I’ve been on Stelara for almost two years."
·
"Stelara or Skyrizi should work for both."
·
"Stelara works very well for both my Crohn’s and psoriasis."
·
"Stelara has been great."
·
"I’ve heard entyvio or stelara has worked for many people with UC."
·
#6

AbbVie

4.4
(13)
"Been on Humira for 7-8 months and it's been a game changer."
·
"No more plaque on my elbows, much smoother skin."
·
"Rinvoq cleared my whole face in 4 days."
·
"Rinvoq changed my life."
·
"I have been using Skyrizi and it has worked 100 percent on my body."
·
"A lot of people in this community have mentioned rinvoq and remicade as options that worked for them."
·
"I would try something like humera or skyrizi first."
·
"Now they have me on Rinvoq. It’s a daily tablet which I love."
·
"So far, I've found the Skyrizi doing a pretty good job."
·
"I took RINVOQ for almost two years. It worked very well."
·
#7

Skyrizi

4.0
(13)
"I am now on Skyrizi and in complete remission."
·
"Skyrizi has given me 100% clearance."
·
"My doctor said it would be the best one from the list I was given."
·
"I have had good luck with Skyrizi and have been taking it for a year."
·
"Other than an odd rash here in there it worked great for inverse."
·
"Took the 2 starter doses and the first maintenance dose and I was about 50% clear and completely gone from the palms by the next dose."
·
"My dr told me skyrizy was shown to be better than stellara."
·
"Skyrizi is promising. Better than stelara"
·
"I wanted to try Skyrizi and she gave me the injection that same day."
·
"I've been on Skyrizi for just 2 weeks now. Genital cleared up about 75% so far. Inverse psoriasis has also cleared up about 75% also."
·
#8

Cosentyx

4.0
(13)
"I second Cosentyx as the most effective of the four biologics I’ve tried!"
·
"I was on Taltz and switched to Cosentyx, never looked back."
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"Cosentyx cleared my skin in a couple of weeks."
·
"On costenyx since August doing much better but fatigue can still raise its head now and again"
·
"I like Cosentyx! My doctor started me on il-17’s first because they had less side effects and I feel so much better!"
·
"Il-17a inhibitor Cosyntex worked better for me than the Enbrel, which wasn't working well when I switched after a half dozen years."
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"I am on cosentyx but i also get hip and shoulder steroid injections every 8months or so and boy do those help!!"
·
"Been on cosentyx now for 4 years and has helped thus far."
·
"People on Cosentyx or Stelara seem to experience less of an increase in colds."
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"From what I have read cosentyx would be the one I would go for given the choice."
·
#9

Janssen

4.5
(10)
"I am currently on Stelara for Crohns. But all my Psoriasis is gone as well as a side bonus."
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"I have been on Stelara for about a year and a half now."
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"I’m on Stelara. Best thing to happen to me."
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"Stelara for 3 years now. Doing great!"
·
"I have been on Stelara for 2 years now and it has worked way better than any other drug I have taken."
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"I must say it does a good job for me with controlling the joints but a bit less on the psoriasis."
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"Tremfya worked much better with my joint issues!"
·
"I take Stelara. It’s great."
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"I definitely prefer the IL-23 inhibitors — Tremfya, Skyrizi, and Ilumya."
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"I’ve seen a huge improvement in my pain level and general mobility."
#10

Cimzia

3.9
(10)
"I’ve been on Cimzia for 6-7 years without issue. It takes care of my AS and my psoriasis."
·
"I’m in (medicated) remission on cimzia for a few years now so I’m pretty happy about that."
·
"Cimzia and Cosentyx were best for me."
·
"I also take Cimzia. Since you’re getting your loading doses, I recommend doing one in your thigh and one in your belly just to see which you like best!"
·
"I’m on Cimzia as well and I always pop an ice pack under my waistband for 30 min before the injection. Don’t feel a thing!"
·
"So far it seems to be working."
·
"I was put on the only biologic that’s pregnancy safe (Cimzia)"
·
"I’m having success so far on Cimzia."
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"When I was on Cimzia I did the belly spots first two doses and then did each thigh for the next two."
·
"Cimzia failed for pain & fatigue"
#11

Dupixent

4.1
(8)
"Been on dupixent three years now, it's been a miracle cure for me!"
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"I’m going to start taking Dupixent soon."
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"It's still better than the severe full body eczema I had before."
·
"I was on Dupixent for a couple of years and it really worked for me."
·
"I personally have had the best luck with dupixent or Adbry for facial flares."
·
"On Dupixent for 6 years and it has worked better for me than any previous medication."
·
"So far have not had any facial flares including eyes."
·
"My son has been on dupixent for 2 years. It has improved his EoE but has done nothing for his EC."
#12

Enbrel

4.2
(6)
"I loved Enbrel! It was my favorite one I've been on."
·
"After ~6 months of experimentation we tried Enbrel. Literally within one hour 99% of my pain disappeared. It was life-changing. It continues to work very well 20 years later."
·
"Worked until it didn't"
·
"When I first started taking Enbrel, I got about 75% better, but still had some pain."
·
"I’ve done Enbrel and Humira in the stomach. It’s super easy and pain free."
·
"I just had my second injection of Enbrel today so it’s too early to tell."
#13

Taltz

3.3
(7)
"Humira and Taltz were best for it."
·
"Taltz finished clearing up my skin."
·
"Taltz does have it's own financial team and they should be reaching out to you soon."
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"For reasons that aren't well understood, even medications that have the same nominal target may have varying effect."
·
"Failed Humira after 3 months. Currently on Taltz (il-17 inhibitor) and feeling great."
·
"I recently switched to Taltz and hope it helps especially my fingernails."
·
"Taltz hasn’t started working yet"
#14

Rinvoq

3.8
(6)
"If it works for you, Rinvoq seems to be the one that people respond to the quickest."
·
"I take rinvoq, it works really well for me."
·
"I also tried dupixent and it helped but I had really itchy eyes."
·
"Rinvoq (Upadacitinib)"
·
"Now on Rinvoq for a couple years and so far it's reasonably good."
·
"Rinvoq has been best for me for the joint related symptoms, but does nothing for the fatigue/brain fog."
#15

Eli Lilly

4.6
(5)
"Taltz took my son from severe total body coverage to clear skin in 2 months."
·
"I’m currently on Taltz, and that cleared me up faster than anything."
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"Taltz was literally miraculous for me."
·
"Taltz worked amazing for me for a long time but sadly stopped working after a little over a year."
·
"Now i’m on olumiant (JAK inhibitors i guess?) working very good."
#16

Simponi

4.0
(5)
"It started working almost right away and I had zero side effects."
·
"Simponi- once a month. Both AS and Crohn’s."
·
"I developed antibodies against humira. Now simponi is working well thanks God"
·
"I started with Cimzia then, humira and now Simponi."
·
"Ive been on cosentyx since august and it hasnt really worked, so im being changed go simponi."
#17

Bimzelx

4.8
(4)
"Ask if Bimzelx is available, it's a newer dual IL-17A and F inhibitor and clinical trials showed really good results."
·
"Bimzelx and Skyrizi are both numerically the most effective in clinical trials."
·
"At the moment I think Bimzelx is at the top..."
·
"IL17 class biologics are worth looking at with Bimzelx the best performing of the class"
#18

Inflectra

4.3
(4)
"Ive been on inflectra for over a year and feel great and in remission."
·
"I've been on Inflectra for 3yrs and I am literally never sick."
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"It gave me my life back."
·
"Was forced to switch to Inflectra (Infliximab-dyyb) per insurance requirements Remission for ~9 months."
#19

Takeda

4.7
(3)
"Entyvio is the most targeted, probably the least likely to have adverse effects."
·
"I’d highly recommend it to anyone who is having a tough time with UC."
·
"I’m on Entyvio, which from my research seemed to have the least side effects."
#20

Novartis

4.3
(3)
"Cosentyx has worked wonderfully for both my psoriasis and psoriatic arthritis since 2017."
·
"Cosentyx cleared it up in 3 doses."
·
"I was then moved to Cosentyx and haven't had a single infection since."
#21

4AllFamily

4.3
(3)
"I used the 4AllFamily travel cooler to keep my Humira cool on a 9 week trip and it worked brilliantly"
·
"4AllFamily has one called RxCooler that's USB-powered. It's not super cheap (the cheapest model is $140), but it may be necessary."
·
"I also use the all4family travel cooler. I like the one with the refrigerated top and battery so I don't have to rely on an outside power source while traveling. It is pricey though."
#22

Tremfya

4.5
(2)
"I started taking Tremfya in January and I am completely clear of all active psoriasis."
·
"I’ve been on biologics changed my life."
#23

Adalimumab

4.5
(2)
"It was life-changing, seriously brought me right back to how I was before I even got UC."
·
"My experience with biologics has been much better- no serious illnesses."
#24

Simponi Aria

4.5
(2)
"Been doing Simponi Aria infusions for about 5 months now and it’s working great! One infusion every 2 months instead of a shot every 2 weeks."
·
"I've had the most relief with the least amount of side effects from Simponi Aria, but it's an IV infusion."
#25

Amgen

4.5
(2)
"Amgevita has been brilliant for me."
·
"I like the weekly dosing of enbrel a lot better for symptom management."
#26

Otezla

5.0
(1)
"When I was in a severe state it cleared everything up so quickly."
#27

Bristol-Myers Squibb

5.0
(1)
"It's been fantastic."
#28

Adbry

5.0
(1)
"Adbry has changed my life."
#29

Orencia

5.0
(1)
"My Orencia is $5 for a few months."
#30

Xeljanz

4.0
(1)
"Xeljanz is working and much more convenient."
#31

Roche

4.0
(1)
"I take Actemra and it works well for me."
#32

Biologic

4.0
(1)
"Sounds like you need to start a new biologic asap."
#33

Amjevita

4.0
(1)
"The first biosimilar, Amjevita, was approved in the US in January 2023."
#34

Vedolizumab

4.0
(1)
"I was on Vedolizumab for 2 years and it was great."
#35

CIBINQO

4.0
(1)
"I believe mine mentioned that CIBINQO (JAK-Inhibitor) would be more effective than Dupixent (Biologic) for facial eczema."
#36

Pentasa

4.0
(1)
"Might be worth trying before you move on to a biologic."
#37

Humerus

4.0
(1)
"Works great"
#38

Modafinil

4.0
(1)
"I’ve been on Modafinil from a sleep doctor for a solid year and it has helped me function"
#39

MedActiv

4.0
(1)
"I wound up purchasing a MedActiv cooler bag to transport three months of Humira to carry me over until I could get my prescription renewed in my new country of residence. It worked well and I’ve since used it a"
#40

Zeljanz

4.0
(1)
"Zeljanz."
#41

VTAMA

4.0
(1)
"VTAMA did work for me very well, but it gave me vertigo so I stopped using it."
#42

Biosimilar

4.0
(1)
"It stopped the severe symptoms pretty much immediately."
#43

Idacio

4.0
(1)
"About to start a Humira biosimilar."
#44

Xolair

4.0
(1)
"Xolair is the most common biologic to go on."
#45

Infliximab

4.0
(1)
"I'd suggest if you are concerned start with Infliximab as it's the oldest and most researched one."
#46

Abrilada

3.0
(1)
"I’m doing my third shot of Abrilada tomorrow. My belly I felt nothing, my thigh really stung!"
#47

Naltrexone

3.0
(1)
"The answer for me was adding low dose naltrexone to my cocktail of meds."
#48

Biological Med

3.0
(1)
"The best biological med is the one that works for you."
#49

Amgevita

2.0
(1)
"Amgevita only kinda half worked for me."

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