r/MTHFR is a subreddit with 33k members. The community frequently discusses mthfr, supplements, methylation, b12, and struggling, and they frequently recommend/review sleep aids, vitamin, and multivitamin, and the most common flair used is question, results discussion, and resource.
This subreddit is dedicated to those wanting to learn more and discuss the MTHFR (Methylene tetra hydro folate reductase) gene mutation.
Popular Topics in r/MTHFR
#1
Mthfr
133 posts
#2
Supplements
60 posts
#3
Methylation
39 posts
#4
B12
32 posts
#5
Struggling
28 posts
#6
Folate
25 posts
#7
Results
24 posts
#8
Advice
21 posts
#9
Anxiety
20 posts
#10
Comt
19 posts
Products Discussed in r/MTHFR
Sleep Aids
6 reviews
#1
Healthy Cell REM Sleep
3.0★ from 1 review
#2
SAMe
4.0★ from 1 review
#3
Meclizine
4.0★ from 1 review
Vitamin
3 reviews
#1
Seeking Health
5.0★ from 2 reviews
#2
10X Health
5.0★ from 1 review
Multivitamin
2 reviews
#1
Seeking Health
4.0★ from 1 review
#2
Thorne
4.0★ from 1 review
Flair Used in r/MTHFR
#1
Question
: "Just started B12 and I am sweating like a MTHFR!"
69 posts
#2
Results Discussion
: "Leaving this sub and simplifying my life was the only thing that fixed my “MTHFR”"
19 posts
#3
Resource
: "Free reference guide to 5 core methylation & folate SNPs (MTHFR, COMT, PEMT) sitting in raw 23andMe/Ancestry data"
5 posts
Member Growth in r/MTHFR
Yearly
+6k members(23.9%)
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Last updated: October 18, 2026